However, negative side effects (skin flushing, stomach upset, diarrhea) usually accompany the supplements, resulting in poor compliance from patients.
Studies have shown that they can increase HDL cholesterol and lower LDL cholesterol and triglycerides. Nicotinic acid supplements contain high amounts, up to 1,000-2,000 mg of niacin taken daily. Bloodwork in someone with dyslipidemia may show high total and LDL “bad” cholesterol levels, low HDL “good” cholesterol, and elevated triglycerides. Niacin and Healthįor more than 40 years, niacin in the form of nicotinic acid has been given to patients to treat a condition called dyslipidemia, a major risk factor for cardiovascular diseases (CVD) such as coronary artery disease, heart attack, and strokes. The UL for niacin for all adults 19+ years is 35 milligrams. UL: The Tolerable Upper Intake Level is the maximum daily intake unlikely to cause harmful effects on health. The Recommended Dietary Allowance (RDA) for adults 19+ years is 16 mg NE for men, 14 mg NE for women, 18 mg NE for pregnant women, and 17 mg NE for lactating women. One NE equals 1 milligram of niacin or 60 mg of tryptophan. RDA: Niacin is measured in milligrams (mg) of niacin equivalents (NE). Niacin helps to convert nutrients into energy, create cholesterol and fats, create and repair DNA, and exert antioxidant effects. Niacin works in the body as a coenzyme, with more than 400 enzymes dependent on it for various reactions. Niacin is water-soluble so that excess amounts the body does not need are excreted in the urine. The body can also convert tryptophan-an amino acid-to nicotinamide. The two most common forms of niacin in food and supplements are nicotinic acid and nicotinamide. Niacin, or vitamin B3, is a water-soluble B vitamin found naturally in some foods, added to foods, and sold as a supplement.
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